Evaluation of prolactin levels in patients with newly diagnosed pemphigus vulgaris and its correlation with pemphigus disease area index

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Evaluation of prolactin levels in patients with newly diagnosed pemphigus vulgaris and its correlation with pemphigus disease area index

BACKGROUND Prolactin is a hormone; in addition to it known roles, it has immunomodulatory effects on lymphocytes maturation and immunoglobulins production. Hyperprolactinemia has been demonstrated in various autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, type I diabetes mellitus, and Graves' disease. In view of the prolactin immunomodulatory roles, studying prol...

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Serum vitamin D level in patients with newly diagnosed pemphigus vulgaris

Background: Pemphigus vulgaris (PV) is a rare autoimmune blistering disease of the skin and mucous membranes. Because vitamin D deficiency is associated with many immune disorders, we compared the levels of vitamin D between PV patients and healthy controls. Methods: Vitamin D level of 20 patients with PV was compared with 20 healthy individuals matched for age, gender, hours spent in the sun, ...

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Quality of life evaluation in patients with pemphigus vulgaris

Background: Pemphigus is a rare autoimmune disease causedby autoantibodies against desmoglein. It clinically presents withpainful blisters and erosions on the skin and mucous membranes.Few studies have been conducted on the quality of life inpemphigus patients which have all indicated the strong impactof the disease on emotional and physical status of the patients.According to evident differenc...

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Desmoglein ELISA in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris.

Anti-desmoglein 3 and 1 autoantibodies are involved in the pathogenesis of pemphigus diseases. Our objective was to assess the value of ELISA in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris. Based on clinical presentation and histopathologic confirmation for the diagnosis of the pemphigus, 38 patients took part in the study. Sera of the patients were te...

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Evaluation of Vitamin D Status in Newly Diagnosed Pemphigus Vulgaris Patients

BACKGROUND Pemphigus vulgaris (PV) is an autoimmune blistering disorder of the skin or mucosa. Since low vitamin D status has been linked to many immune disorders, we designed this study to compare the vitamin D status in PV patients with healthy controls. METHODS In this case-control study, vitamin D status of 32 newly diagnosed PV patients was compared with 36 healthy control subjects. All ...

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ژورنال

عنوان ژورنال: International Journal of Women's Dermatology

سال: 2016

ISSN: 2352-6475

DOI: 10.1016/j.ijwd.2016.02.004